Description: This talk presents the ongoing work of the I.Sicily and Crossreads projects. I.Sicily is a multilingual digital corpus of the inscriptions of ancient Sicily based upon fresh autopsy (sicily.classics.ox.ac.uk); Crossreads is 5-year ERC project developing and applying linguistic, palaeographic and archaeometric analyses to this corpus (crossreads.web.ox.ac.uk). The ambition of both projects is to make the complex epigraphic heritage of Sicily more accessible and to cast new light upon the cultural history of Sicily through this rich corpus of evidence. The talk will explore some of the methodological challenges and present some of the results achieved so far.